Peyton Jacob, PhD, a research chemist for the Division of Clinical Pharmacology in the Department of Medicine, and is a longtime collaborator with Dr. Benowitz.  He directs the Clinical Pharmacology Lab at the Zuckerburg San Francisco General Hospital (ZSFG).  Under his supervision, the lab is staffed with 10 research personell.  The Laboratory is equipped with three triple-quadrupole mass spectrometers (both GC and LC interfaces), a desktop GC-MS system, HPLCs and GCs. The CPL typically analyzes 10,000-15,000 samples annually.